If you pour the sugar right after the hot water the energy disparity between the molecules of the water and those of the sugar might lead to tearing down molecules which on its behalf might lead to tearing down atoms(if the water is being heated for at least minute and a half in the microwave and the sugar has been in the fridge the whole time - a too great of energy disparity)
Therefore leading to a nuclear reaction with enormous energies released. You can literally blow up your town if you add the sugar right after the very hot water.